Application
SIRT5 Antibody (Center) western blot analysis in human placenta tissue lysates (35ug/lane).This demonstrates the SIRT5 antibody detected the SIRT5 protein (arrow).Application
Western blot analysis of SIRT5 (arrow) using rabbit polyclonal SIRT5 Antibody (Center) . 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the SIRT5 gene.| Product Name | SIRT5 Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | SIR2L5 |
|---|---|
| Alternative Names | SIRT5 SIR2L5 NAD-dependent protein deacylase sirtuin-5 mitochondrial Regulatory protein SIR2 homolog 5 SIR2-like protein 5 |
| Molecular Weight(MW) | 33881 Da |
| Function | NAD-dependent lysine demalonylase and desuccinylase that specifically removes malonyl and succinyl groups on target proteins. Activates CPS1 and contributes to the regulation of blood ammonia levels during prolonged fasting: acts by mediating desuccinylation of CPS1, thereby increasing CPS1 activity in response to elevated NAD levels during fasting. Has weak NAD- dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo. Can deacetylate cytochrome c (CYCS) and a number of other proteins in vitro |
| Tissue Specificity | Widely expressed. |
| Cellular Localization | Mitochondrion matrix. Mitochondrion intermembrane space Isoform 2: Mitochondrion. |
| Entrez Gene | 23408 |
|---|---|
| Nucleotide Accession | NP_036373.1 NP_112534.1 |
Application
SIRT5 Antibody (Center) western blot analysis in human placenta tissue lysates (35ug/lane).This demonstrates the SIRT5 antibody detected the SIRT5 protein (arrow).
Application
Western blot analysis of SIRT5 (arrow) using rabbit polyclonal SIRT5 Antibody (Center) . 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the SIRT5 gene.| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
