Application
SIRT4 Antibody (N-term) western blot analysis in mouse testis tissue lysates (35ug/lane).This demonstrates the SIRT4 antibody detected the SIRT4 protein (arrow).| Product Name | SIRT4 Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | SIR2L4 |
|---|---|
| Alternative Names | SIRT4 SIR2L4 NAD-dependent protein deacetylase sirtuin-4 NAD-dependent ADP-ribosyltransferase sirtuin-4 Regulatory protein SIR2 homolog 4 SIR2-like protein 4 |
| Molecular Weight(MW) | 35188 Da |
| Function | NAD-dependent protein ADP-ribosyl transferase. Catalyzes the transfer of ADP-ribosyl groups onto target proteins, including mitochondrial GLUD1. Inhibits GLUD1 enzyme activity. Down- regulates insulin secretion. Has no detectable protein deacetylase activity |
| Tissue Specificity | Detected in vascular smooth muscle and striated muscle. Detected in insulin-producing beta-cells in pancreas islets of Langerhans (at protein level). Widely expressed. Weakly expressed in leukocytes and fetal thymus |
| Cellular Localization | Mitochondrion matrix. |
| Entrez Gene | 23409 |
|---|---|
| Nucleotide Accession | NP_036372.1 |
Application
SIRT4 Antibody (N-term) western blot analysis in mouse testis tissue lysates (35ug/lane).This demonstrates the SIRT4 antibody detected the SIRT4 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
