Application
SLC4A7 Antibody (C-term) western blot analysis in K562 cell line lysates (15ug/lane).This demonstrates the SLC4A7 antibody detected the SLC4A7 protein (arrow).Application
SLC4A7 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human spleen tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the SLC4A7 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Product Name | SLC4A7 Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | SLC4A7; BT; NBC2; NBC2B; NBC3; SBC2; SLC4A6; Sodium bicarbonate cotransporter 3; Sodium bicarbonate cotransporter 2; Sodium bicarbonate cotransporter 2b; Solute carrier family 4 member 7 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | BT NBC2 NBC2B NBC3 SBC2 SLC4A6 |
|---|---|
| Alternative Names | SLC4A7 BT NBC2 NBC2B NBC3 SBC2 SLC4A6 Sodium bicarbonate cotransporter 3 Sodium bicarbonate cotransporter 2 Sodium bicarbonate cotransporter 2b Solute carrier family 4 member 7 |
| Molecular Weight(MW) | 136044 Da |
| Function | Electroneutral sodium- and bicarbonate-dependent cotransporter with a Na(+):HCO3(-) 1:1 stoichiometry. Regulates intracellular pH and may play a role in bicarbonate salvage in secretory epithelia. May also have an associated sodium channel activity |
| Tissue Specificity | Highly expressed in testis and spleen. Also expressed in retina, colon, small intestine, ovary, thymus, prostate, muscle, heart and kidney. Isoform 1 is expressed in skeletal muscle and heart muscle |
| Cellular Localization | Basolateral cell membrane; Multi-pass membrane protein. Apical cell membrane; Multi-pass membrane protein (By similarity). Cell projection, stereocilium (By similarity). Note=Also described at the apical cell membrane Localizes to the stereocilia of cochlear outer hair cells and to the lateral membrane of cochlear inner hair cells (By similarity) |
| Entrez Gene | 9497 |
|---|---|
| Nucleotide Accession | NP_003606.3 |
Application
SLC4A7 Antibody (C-term) western blot analysis in K562 cell line lysates (15ug/lane).This demonstrates the SLC4A7 antibody detected the SLC4A7 protein (arrow).
Application
SLC4A7 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human spleen tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the SLC4A7 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
