Application
SLC6A4 Antibody (Center) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the SLC6A4 antibody detected the SLC6A4 protein (arrow).| Product Name | SLC6A4 Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | SLC6A4; HTT; SERT; Sodium-dependent serotonin transporter; 5HT transporter; Solute carrier family 6 member 4 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | HTT SERT |
|---|---|
| Alternative Names | SLC6A4 HTT SERT Sodium-dependent serotonin transporter 5HT transporter Solute carrier family 6 member 4 |
| Molecular Weight(MW) | 70325 Da |
| Function | Serotonin transporter whose primary function in the central nervous system involves the regulation of serotonergic signaling via transport of serotonin molecules from the synaptic cleft back into the pre-synaptic terminal for re-utilization Plays a key role in mediating regulation of the availability of serotonin to other receptors of serotonergic systems. Terminates the action of serotonin and recycles it in a sodium-dependent manner |
| Tissue Specificity | Expressed in platelets (at protein level). |
| Cellular Localization | Cell membrane; Multi-pass membrane protein. Endomembrane system; Multi-pass membrane protein. Endosome membrane; Multi-pass membrane protein. Note=Translocates from intracellular locations to the plasma membrane. Density of transporter molecules on the plasma membrane is itself regulated by serotonin |
| Entrez Gene | 6532 |
|---|---|
| Nucleotide Accession | NP_001036.1 |
Application
SLC6A4 Antibody (Center) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the SLC6A4 antibody detected the SLC6A4 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
