Application
Western blot analysis of SLCO1B1 Antibody (Center) in HepG2 cell line lysates (35ug/lane). SLCO1B1 (arrow) was detected using the purified Pab.| Product Name | SLCO1B1 Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | SLCO1B1; LST1; OATP1B1; OATP2; OATPC; SLC21A6; Solute carrier organic anion transporter family member 1B1; Liver-specific organic anion transporter 1; OATP-C; Sodium-independent organic anion-transporting polypeptide 2; Solute carrier family 21 member 6 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | LST1 OATP1B1 OATP2 OATPC SLC21A6 |
|---|---|
| Alternative Names | SLCO1B1 LST1 OATP1B1 OATP2 OATPC SLC21A6 Solute carrier organic anion transporter family member 1B1 Liver-specific organic anion transporter 1 OATP-C Sodium-independent organic anion-transporting polypeptide 2 Solute carrier family 21 member 6 |
| Molecular Weight(MW) | 76449 Da |
| Function | Mediates the Na(+)-independent uptake of organic anions such as pravastatin, taurocholate, methotrexate, dehydroepiandrosterone sulfate, 17-beta-glucuronosyl estradiol, estrone sulfate, prostaglandin E2, thromboxane B2, leukotriene C3, leukotriene E4, thyroxine and triiodothyronine. Involved in the clearance of bile acids and organic anions from the liver |
| Tissue Specificity | Highly expressed in liver, at the basolateral membranes of centrilobular hepatocytes. Not detected in heart, brain, placenta, lung, skeletal muscle, kidney, pancreas, spleen, thymus, prostate, testis, ovary, small intestine, colon and leukocyte |
| Cellular Localization | Basolateral cell membrane; Multi-pass membrane protein. Note=Detected in basolateral membranes of hepatocytes |
| Entrez Gene | 10599 |
|---|
Application
Western blot analysis of SLCO1B1 Antibody (Center) in HepG2 cell line lysates (35ug/lane). SLCO1B1 (arrow) was detected using the purified Pab.| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
