Application
SNX18 Antibody (C-term) western blot analysis in WiDr cell line lysates (35ug/lane).This demonstrates the SNX18 antibody detected the SNX18 protein (arrow).| Product Name | SNX18 Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | SNX18; SH3PXD3B; SNAG1; Sorting nexin-18; SH3 and PX domain-containing protein 3B; Sorting nexin-associated Golgi protein 1 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | SH3PXD3B SNAG1 |
|---|---|
| Alternative Names | SNX18 SH3PXD3B SNAG1 Sorting nexin-18 SH3 and PX domain-containing protein 3B Sorting nexin-associated Golgi protein 1 |
| Molecular Weight(MW) | 68894 Da |
| Function | May be involved in several stages of intracellular trafficking. Plays a role in endocytosis via clathrin-coated pits, but also clathrin-independent, actin-dependent fluid-phase endocytosis. Plays a role in macropinocytosis. Binds to membranes enriched in phosphatidylinositol 4,5-bisphosphate and promotes membrane tubulation. Stimulates the GTPase activity of DNM2 Promotes DNM2 location at the plasma membrane |
| Tissue Specificity | This SNX18 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 484-514 amino acids from the C-terminal region of human SNX18. |
| Cellular Localization | Endomembrane system; Peripheral membrane protein; Cytoplasmic side. Endosome membrane; Peripheral membrane protein; Cytoplasmic side. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Note=Localized at sites of endocytosis at the cell membrane. Detected on newly formed macropinosomes Partially colocalized with clathrin and dynamin at the cell membrane. Transiently recruited to clathrin-coated pits at a late stage of clathrin-coated vesicle formation |
| Entrez Gene | 112574 |
|---|---|
| Nucleotide Accession | NP_001096045.1 NP_001138899.1 |
Application
SNX18 Antibody (C-term) western blot analysis in WiDr cell line lysates (35ug/lane).This demonstrates the SNX18 antibody detected the SNX18 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
