Application
SSH1 Antibody (N-term) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the SSH1 antibody detected the SSH1 protein (arrow).| Product Name | SSH1 (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | SSH1; KIAA1298; SSH1L; Protein phosphatase Slingshot homolog 1; SSH-like protein 1 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | KIAA1298 SSH1L |
|---|---|
| Alternative Names | SSH1 KIAA1298 SSH1L Protein phosphatase Slingshot homolog 1 SSH-like protein 1 |
| Molecular Weight(MW) | 115511 Da |
| Function | Protein phosphatase which regulates actin filament dynamics. Dephosphorylates and activates the actin binding/depolymerizing factor cofilin, which subsequently binds to actin filaments and stimulates their disassembly. Inhibitory phosphorylation of cofilin is mediated by LIMK1, which may also be dephosphorylated and inactivated by this protein |
| Tissue Specificity | This SSH1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 226-254 amino acids from the N-terminal region of human SSH1. |
| Cellular Localization | Cytoplasm, cytoskeleton. Cell projection, lamellipodium. Cleavage furrow. Midbody. Note=Also recruited to actin rich membrane protrusions such as lamellipodia, which may allow local control of actin dynamics at sites of cell locomotion Also localized to the cleavage furrow and the midbody during cytokinesis |
| Entrez Gene | 54434 |
|---|---|
| Nucleotide Accession | NP_061857.3 |
Application
SSH1 Antibody (N-term) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the SSH1 antibody detected the SSH1 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
