Application
SUZ12 Antibody (C-term) western blot analysis in Ramos cell line lysates (35ug/lane).This demonstrates the SUZ12 antibody detected the SUZ12 protein (arrow).| Product Name | SUZ12 Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | SUZ12;CHET9; JJAZ1; KIAA0160; Polycomb protein SUZ12; Polycomb protein SUZ12; Chromatin precipitated E2F target 9 protein; Polycomb protein SUZ12; Joined to JAZF1 protein; Polycomb protein SUZ12; Suppressor of zeste 12 protein homolog |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | CHET9 JJAZ1 KIAA0160 |
|---|---|
| Alternative Names | SUZ12 CHET9 JJAZ1 KIAA0160 Polycomb protein SUZ12 Polycomb protein SUZ12 Chromatin precipitated E2F target 9 protein Polycomb protein SUZ12 Joined to JAZF1 protein Polycomb protein SUZ12 Suppressor of zeste 12 protein homolog |
| Molecular Weight(MW) | 83055 Da |
| Function | Polycomb group (PcG) protein. Component of the PRC2/EED- EZH2 complex, which methylates 'Lys-9' (H3K9me) and 'Lys-27' (H3K27me) of histone H3, leading to transcriptional repression of the affected target gene. The PRC2/EED-EZH2 complex may also serve as a recruiting platform for DNA methyltransferases, thereby linking two epigenetic repression systems. Genes repressed by the PRC2/EED-EZH2 complex include HOXC8, HOXA9, MYT1 and CDKN2A |
| Tissue Specificity | Overexpressed in breast and colon cancer. |
| Cellular Localization | Nucleus. |
| Entrez Gene | 23512 |
|---|
Application
SUZ12 Antibody (C-term) western blot analysis in Ramos cell line lysates (35ug/lane).This demonstrates the SUZ12 antibody detected the SUZ12 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
