Application
A. Western blot analysis on (A) A431 and (B) fetal small intestine lysates using anti-TCF-3 RabMAb (Cat. #AJ1759a), dilution 1:2000.| Product Name | TCF-3 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | TCF7L1, TCF3, Transcription factor 7-like 1, HMG box transcription factor 3 |
| Clonality | Monoclonal |
|---|---|
| Clone Number | EPR2031 |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:1000~5000 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | TCF3 |
|---|---|
| Alternative Names | TCF7L1 TCF3 Transcription factor 7-like 1 HMG box transcription factor 3 |
| Molecular Weight(MW) | 62631 Da |
| Function | Participates in the Wnt signaling pathway. Binds to DNA and acts as a repressor in the absence of CTNNB1, and as an activator in its presence. Necessary for the terminal differentiation of epidermal cells, the formation of keratohyalin granules and the development of the barrier function of the epidermis (By similarity). Down-regulates NQO1, leading to increased mitomycin c resistance |
| Tissue Specificity | Detected in hair follicles and skin keratinocytes, and at lower levels in stomach epithelium |
| Cellular Localization | Nucleus. |
| Entrez Gene | 83439 |
|---|
Application
A. Western blot analysis on (A) A431 and (B) fetal small intestine lysates using anti-TCF-3 RabMAb (Cat. #AJ1759a), dilution 1:2000.| Application Notes | WB:1:1000~5000 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. |
