Application
TGFB1I1 Antibody (N-term) western blot analysis in mouse kidney tissue lysates (35ug/lane).This demonstrates the TGFB1I1 antibody detected the TGFB1I1 protein (arrow).Application
TGFB1I1 Antibody (N-term) (AP14684a)immunohistochemistry analysis in formalin fixed and paraffin embedded human testis tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of TGFB1I1 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Product Name | TGFB1I1 Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | ARA55 |
|---|---|
| Alternative Names | TGFB1I1 ARA55 Transforming growth factor beta-1-induced transcript 1 protein Androgen receptor coactivator 55 kDa protein Androgen receptor-associated protein of 55 kDa Hydrogen peroxide-inducible clone 5 protein |
| Molecular Weight(MW) | 49814 Da |
| Function | Functions as a molecular adapter coordinating multiple protein-protein interactions at the focal adhesion complex and in the nucleus. Links various intracellular signaling modules to plasma membrane receptors and regulates the Wnt and TGFB signaling pathways. May also regulate SLC6A3 and SLC6A4 targeting to the plasma membrane hence regulating their activity. In the nucleus, functions as a nuclear receptor coactivator regulating glucocorticoid, androgen, mineralocorticoid and progesterone receptor transcriptional activity. May play a role in the processes of cell growth, proliferation, migration, differentiation and senescence. May have a zinc-dependent DNA- binding activity |
| Tissue Specificity | Expressed in platelets, smooth muscle and prostate stromal cells (at protein level) |
| Cellular Localization | Cell junction, focal adhesion. Nucleus matrix. Cytoplasm, cytoskeleton. Note=Associated with the actin cytoskeleton; colocalizes with stress fibers |
| Entrez Gene | 7041 |
|---|---|
| Nucleotide Accession | NP_001035919.1 NP_001158191.1 |
Application
TGFB1I1 Antibody (N-term) western blot analysis in mouse kidney tissue lysates (35ug/lane).This demonstrates the TGFB1I1 antibody detected the TGFB1I1 protein (arrow).
Application
TGFB1I1 Antibody (N-term) (AP14684a)immunohistochemistry analysis in formalin fixed and paraffin embedded human testis tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of TGFB1I1 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
