Application
TRAFD1 Antibody (C-term) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the TRAFD1 antibody detected the TRAFD1 protein (arrow).| Product Name | TRAFD1 Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | TRAFD1; FLN29; TRAF-type zinc finger domain-containing protein 1; Protein FLN29 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | FLN29 |
|---|---|
| Alternative Names | TRAFD1 FLN29 TRAF-type zinc finger domain-containing protein 1 Protein FLN29 |
| Molecular Weight(MW) | 64841 Da |
| Function | Negative feedback regulator that controls excessive innate immune responses. Regulates both Toll-like receptor 4 (TLR4) and DDX58/RIG1-like helicases (RLH) pathways. May inhibit the LTR pathway by direct interaction with TRAF6 and attenuation of NF-kappa-B activation. May negatively regulate the RLH pathway downstream from MAVS and upstream of NF-kappa-B and IRF3 (By similarity) |
| Tissue Specificity | This TRAFD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 541-569 amino acids from the C-terminal region of human TRAFD1. |
| Entrez Gene | 10906 |
|---|---|
| Nucleotide Accession | NP_001137378.1 NP_006691.1 |
Application
TRAFD1 Antibody (C-term) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the TRAFD1 antibody detected the TRAFD1 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
