Application
TRAIL Antibody (Center N109) western blot analysis in MDA-MB435 cell line lysates (35ug/lane).This demonstrates the TRAIL antibody detected the TRAIL protein (arrow).Application
Confocal immunofluorescent analysis of TRAIL Antibody (Center N109) with Hela cell followed by Alexa Fluor® 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).Application
TRAIL Antibody (Center N109) immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of TRAIL Antibody (Center N109) for immunohistochemistry. Clinical relevance has not been evaluated.| Product Name | TRAIL Antibody (Center N109) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | TNFSF10; APO2L; TRAIL; Tumor necrosis factor ligand superfamily member 10; Apo-2 ligand; TNF-related apoptosis-inducing ligand; CD_antigen=CD253 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIFIHC |
| WB:1:100~500 IF |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | APO2L TRAIL |
|---|---|
| Alternative Names | TNFSF10 APO2L TRAIL Tumor necrosis factor ligand superfamily member 10 Apo-2 ligand TNF-related apoptosis-inducing ligand CD_antigen=CD253 |
| Molecular Weight(MW) | 32509 Da |
| Function | Cytokine that binds to TNFRSF10A/TRAILR1, TNFRSF10B/TRAILR2, TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4 and possibly also to TNFRSF11B/OPG. Induces apoptosis. Its activity may be modulated by binding to the decoy receptors TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4 and TNFRSF11B/OPG that cannot induce apoptosis |
| Tissue Specificity | Widespread; most predominant in spleen, lung and prostate |
| Cellular Localization | Membrane; Single-pass type II membrane protein (Potential) |
| Entrez Gene | 8743 |
|---|---|
| Nucleotide Accession | NP_003801.1 |
Application
TRAIL Antibody (Center N109) western blot analysis in MDA-MB435 cell line lysates (35ug/lane).This demonstrates the TRAIL antibody detected the TRAIL protein (arrow).
Application
Confocal immunofluorescent analysis of TRAIL Antibody (Center N109) with Hela cell followed by Alexa Fluor® 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).
Application
TRAIL Antibody (Center N109) immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of TRAIL Antibody (Center N109) for immunohistochemistry. Clinical relevance has not been evaluated.| Application Notes | WB:1:100~500 IF |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
