TRIM56 Antibody (C-term) western blot analysis in A375 cell line lysates (35ug/lane).This demonstrates the TRIM56 antibody detected the TRIM56 protein (arrow).
TRIM56; RNF109; E3 ubiquitin-protein ligase TRIM56; RING finger protein 109; Tripartite motif-containing protein 56
Key Feature
Clonality
Polyclonal
Isotype
Ig
Host Species
Rabbit
Tested Applications
WB
WB:1:100~500
Species Reactivity
Human
Concentration
1mg/ml
Target Information
Gene Synonyms
RNF109
Alternative Names
TRIM56 RNF109 E3 ubiquitin-protein ligase TRIM56 RING finger protein 109 Tripartite motif-containing protein 56
Molecular Weight(MW)
81488 Da
Function
E3 ubiquitin-protein ligase that mediates 'Lys-63'- linked polyubiquitination of TMEM173/STING, thereby playing a key role in innate immunity. TMEM173/STING 'Lys-63'-linked ubiquitination activates the production of type I interferon IFN- beta following detection of pathogen- and host-derived double- stranded DNA (By similarity)
Tissue Specificity
This TRIM56 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 724-755 amino acids from the C-terminal region of human TRIM56.
TRIM56 Antibody (C-term) western blot analysis in A375 cell line lysates (35ug/lane).This demonstrates the TRIM56 antibody detected the TRIM56 protein (arrow).
Application Notes
WB:1:100~500
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.