Application
TRMU Antibody (Center) western blot analysis in MDA-MB453 cell line lysates (35ug/lane).This demonstrates the TRMU antibody detected the TRMU protein (arrow).| Product Name | TRMU Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | TRMU; MTU1; TRMT1; Mitochondrial tRNA-specific 2-thiouridylase 1; MTO2 homolog |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | MTU1 TRMT1 |
|---|---|
| Alternative Names | TRMU MTU1 TRMT1 Mitochondrial tRNA-specific 2-thiouridylase 1 MTO2 homolog |
| Molecular Weight(MW) | 47745 Da |
| Function | Catalyzes the 2-thiolation of uridine at the wobble position (U34) of mitochondrial tRNA(Lys), tRNA(Glu) and tRNA(Gln). Required for the formation of 5-taurinomethyl-2- thiouridine (tm5s2U) of mitochondrial tRNA(Lys), tRNA(Glu), and tRNA(Gln) at the wobble position. ATP is required to activate the C2 atom of the wobble base |
| Tissue Specificity | Ubiquitous. Abundantly expressed in tissues with high metabolic rates including heart, liver, kidney, and brain |
| Cellular Localization | Mitochondrion. |
| Entrez Gene | 55687 |
|---|---|
| Nucleotide Accession | NP_060476.2 |
Application
TRMU Antibody (Center) western blot analysis in MDA-MB453 cell line lysates (35ug/lane).This demonstrates the TRMU antibody detected the TRMU protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
