Application
Western blot analysis of hTRKC-C45 in 293 cell line lysates (35ug/lane). TRKC (arrow) was detected using the purified Pab.Application
Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.| Product Name | TRKC Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | NTRK3; TRKC; NT-3 growth factor receptor; GP145-TrkC; Neurotrophic tyrosine kinase receptor type 3; TrkC tyrosine kinase |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | TRKC |
|---|---|
| Alternative Names | NTRK3 TRKC NT-3 growth factor receptor GP145-TrkC Neurotrophic tyrosine kinase receptor type 3 TrkC tyrosine kinase |
| Molecular Weight(MW) | 94428 Da |
| Function | Receptor for neurotrophin-3 (NT-3). This is a tyrosine- protein kinase receptor. Known substrates for the trk receptors are SHC1, PI-3 kinase, and PLCG1. The different isoforms do not have identical signaling properties |
| Tissue Specificity | Widely expressed but mainly in nervous tissue. Isoform B is expressed at higher levels in adult brain than in fetal brain |
| Cellular Localization | Membrane; Single-pass type I membrane protein |
| Entrez Gene | 4916 |
|---|
Application
Western blot analysis of hTRKC-C45 in 293 cell line lysates (35ug/lane). TRKC (arrow) was detected using the purified Pab.
Application
Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
