Application
CHAK2 Antibody (H332) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the CHAK2 antibody detected the CHAK2 protein (arrow).Application
TRPM6(CHAK2) Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of TRPM6 Antibody (CHAK2) (Center) for immunohistochemistry. Clinical relevance has not been evaluated.| Product Name | TRPM6 (CHAK2) Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | TRPM6; CHAK2; Transient receptor potential cation channel subfamily M member 6; Channel kinase 2; Melastatin-related TRP cation channel 6 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | CHAK2 |
|---|---|
| Alternative Names | TRPM6 CHAK2 Transient receptor potential cation channel subfamily M member 6 Channel kinase 2 Melastatin-related TRP cation channel 6 |
| Molecular Weight(MW) | 231708 Da |
| Function | Essential ion channel and serine/threonine-protein kinase. Crucial for magnesium homeostasis. Has an important role in epithelial magnesium transport and in the active magnesium absorption in the gut and kidney. Isoforms of the type M6-kinase lack the ion channel region |
| Tissue Specificity | Highly expressed in kidney and colon. Isoform TRPM6a and isoform TRPM6b, are coexpressed with TRPM7 in kidney, and testis, and are also found in several cell lines of lung origin. Isoform TRPM6c is detected only in testis and in NCI-H510A small cell lung carcinoma cells |
| Cellular Localization | Membrane; Multi-pass membrane protein. |
| Entrez Gene | 140803 |
|---|
Application
CHAK2 Antibody (H332) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the CHAK2 antibody detected the CHAK2 protein (arrow).
Application
TRPM6(CHAK2) Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of TRPM6 Antibody (CHAK2) (Center) for immunohistochemistry. Clinical relevance has not been evaluated.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
