Application
TYRP1 Antibody (Center) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the TYRP1 antibody detected the TYRP1 protein (arrow).| Product Name | TYRP1 Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | TYRP1; CAS2; TYRP; TYRRP; 5, 6-dihydroxyindole-2-carboxylic acid oxidase; Catalase B; Glycoprotein 75; Melanoma antigen gp75; Tyrosinase-related protein 1 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | CAS2 TYRP TYRRP |
|---|---|
| Alternative Names | TYRP1 CAS2 TYRP TYRRP 5 6-dihydroxyindole-2-carboxylic acid oxidase Catalase B Glycoprotein 75 Melanoma antigen gp75 Tyrosinase-related protein 1 |
| Molecular Weight(MW) | 60724 Da |
| Function | Oxidation of 5,6-dihydroxyindole-2-carboxylic acid (DHICA) into indole-5,6-quinone-2-carboxylic acid. May regulate or influence the type of melanin synthesized |
| Tissue Specificity | Pigment cells. |
| Cellular Localization | Melanosome membrane; Single-pass type I membrane protein (By similarity). Note=Located to mature stage III and IV melanosomes and apposed endosomal tubular membranes Transported to pigmented melanosomes by the BLOC-1 complex (By similarity) |
| Entrez Gene | 7306 |
|---|---|
| Nucleotide Accession | NP_000541.1 |
Application
TYRP1 Antibody (Center) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the TYRP1 antibody detected the TYRP1 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
