Application
VDR Antibody (Center) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the VDR antibody detected the VDR protein (arrow).Application
VDR Antibody (Center) flow cytometric analysis of Hela cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated donkey-anti-rabbit secondary antibodies were used for the analysis.| Product Name | VDR Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBFC |
| WB:1:100~500 FC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | NR1I1 |
|---|---|
| Alternative Names | VDR NR1I1 Vitamin D3 receptor 1 25-dihydroxyvitamin D3 receptor Nuclear receptor subfamily 1 group I member 1 |
| Molecular Weight(MW) | 48289 Da |
| Function | Nuclear hormone receptor. Transcription factor that mediates the action of vitamin D3 by controlling the expression of hormone sensitive genes. Regulates transcription of hormone sensitive genes via its association with the WINAC complex, a chromatin-remodeling complex. Recruited to promoters via its interaction with the WINAC complex subunit BAZ1B/WSTF, which mediates the interaction with acetylated histones, an essential step for VDR-promoter association. Plays a central role in calcium homeostasis |
| Tissue Specificity | This VDR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 273-299 amino acids from the Central region of human VDR. |
| Cellular Localization | Nucleus. |
| Entrez Gene | 7421 |
|---|---|
| Nucleotide Accession | NP_001017535.1 NP_000367.1 |
Application
VDR Antibody (Center) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the VDR antibody detected the VDR protein (arrow).
Application
VDR Antibody (Center) flow cytometric analysis of Hela cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated donkey-anti-rabbit secondary antibodies were used for the analysis.| Application Notes | WB:1:100~500 FC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
