Application
WDR5 Antibody (N-term) western blot analysis in A2058 cell line lysates (35ug/lane).This demonstrates the WDR5 antibody detected the WDR5 protein (arrow).| Product Name | WDR5 Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | WDR5; BIG3; WD repeat-containing protein 5; BMP2-induced 3-kb gene protein |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | BIG3 |
|---|---|
| Alternative Names | WDR5 BIG3 WD repeat-containing protein 5 BMP2-induced 3-kb gene protein |
| Molecular Weight(MW) | 36588 Da |
| Function | Contributes to histone modification. May position the N- terminus of histone H3 for efficient trimethylation at 'Lys-4'. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues May regulate osteoblasts differentiation |
| Tissue Specificity | This WDR5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 11-40 amino acids from the N-terminal region of human WDR5. |
| Cellular Localization | Nucleus. |
| Entrez Gene | 11091 |
|---|---|
| Nucleotide Accession | NP_060058.1 NP_438172.1 |
Application
WDR5 Antibody (N-term) western blot analysis in A2058 cell line lysates (35ug/lane).This demonstrates the WDR5 antibody detected the WDR5 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
