Application
Western blot analysis of YEATS4 (arrow) using rabbit polyclonal YEATS4 Antibody . 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the YEATS4 gene.| Product Name | YEATS4 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | YEATS4; GAS41; YEATS domain-containing protein 4; Glioma-amplified sequence 41; NuMA-binding protein 1 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | GAS41 |
|---|---|
| Alternative Names | YEATS4 GAS41 YEATS domain-containing protein 4 Glioma-amplified sequence 41 NuMA-binding protein 1 |
| Molecular Weight(MW) | 26499 Da |
| Function | Component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. NuA4 may also play a direct role in DNA repair when recruited to sites of DNA damage |
| Tissue Specificity | Expressed in brain, heart, kidney, liver, lung, pancreas, placenta and skeletal muscle |
| Cellular Localization | Nucleus. |
| Entrez Gene | 8089 |
|---|---|
| Nucleotide Accession | NP_006521.1 |
Application
Western blot analysis of YEATS4 (arrow) using rabbit polyclonal YEATS4 Antibody . 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the YEATS4 gene.| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
