Application
ABCC6 Antibody (C-term) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the ABCC6 antibody detected the ABCC6 protein (arrow).Application
ABCC6 antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of the ABCC6 antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Product Name | ABCC6 Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | ABCC6; ARA; MRP6; Multidrug resistance-associated protein 6; ATP-binding cassette sub-family C member 6; Anthracycline resistance-associated protein; Multi-specific organic anion transporter E |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | ARA MRP6 |
|---|---|
| Alternative Names | ABCC6 ARA MRP6 Multidrug resistance-associated protein 6 ATP-binding cassette sub-family C member 6 Anthracycline resistance-associated protein Multi-specific organic anion transporter E |
| Molecular Weight(MW) | 164906 Da |
| Function | May participate directly in the active transport of drugs into subcellular organelles or influence drug distribution indirectly. Transports glutathione conjugates as leukotriene-c4 (LTC4) and N-ethylmaleimide S-glutathione (NEM-GS) |
| Tissue Specificity | Expressed in kidney and liver. Very low expression in other tissues |
| Cellular Localization | Membrane; Multi-pass membrane protein (By similarity). Note=Localized to the basolateral membrane |
| Entrez Gene | 368 |
|---|---|
| Nucleotide Accession | NP_001162.4 |
Application
ABCC6 Antibody (C-term) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the ABCC6 antibody detected the ABCC6 protein (arrow).
Application
ABCC6 antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of the ABCC6 antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Data sheet for OM225594