Application
A.Western blot analysis on Hela cell lysate using anti-Bad (N-term) RabMAb (Cat. #AJ1074a), dilution 1:5,000.Application
B. Immunohistochemical staining of paraffin-embedded human lymphoma using anti-Bad (N-term) RabMAb (Cat. #AJ1074a)Application
C. Immunohistochemical staining of paraffin-embedded human lymphoma using a anti-Bad (N-term) RabMAb (Cat. #AJ1074a)| Product Name | Bad Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Monoclonal |
|---|---|
| Clone Number | Y208 |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:10000 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | BBC6, BCL2L8 |
|---|---|
| Alternative Names | BAD BBC6 BCL2L8 Bcl2 antagonist of cell death Bcl-XL/Bcl-2-associated death promoter |
| Molecular Weight(MW) | 18392 Da |
| Function | Promotes cell death. Successfully competes for the binding to Bcl-X(L), Bcl-2 and Bcl-W, thereby affecting the level of heterodimerization of these proteins with BAX. Can reverse the death repressor activity of Bcl-X(L), but not that of Bcl-2 (By similarity). Appears to act as a link between growth factor receptor signaling and the apoptotic pathways |
| Tissue Specificity | Expressed in a wide variety of tissues. |
| Cellular Localization | Mitochondrion outer membrane. Cytoplasm. Note=Upon phosphorylation, locates to the cytoplasm |
| Entrez Gene | 572 |
|---|
Application
A.Western blot analysis on Hela cell lysate using anti-Bad (N-term) RabMAb (Cat. #AJ1074a), dilution 1:5,000.
Application
B. Immunohistochemical staining of paraffin-embedded human lymphoma using anti-Bad (N-term) RabMAb (Cat. #AJ1074a)
Application
C. Immunohistochemical staining of paraffin-embedded human lymphoma using a anti-Bad (N-term) RabMAb (Cat. #AJ1074a)| Application Notes | WB:1:10000 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. |
