Application
Western blot analysis of anti-BMPR1A Pab (Cat. #ap2004a) in Saos-2 cell lysate. BMPR1A (arrow) was detected using purified Pab. Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence.| Product Name | BMPR1A Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | BMPR1A; ACVRLK3; ALK3; Bone morphogenetic protein receptor type-1A; Activin receptor-like kinase 3; Serine/threonine-protein kinase receptor R5; CD_antigen=CD292; Flags: Precursor |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | ACVRLK3 ALK3 |
|---|---|
| Alternative Names | BMPR1A ACVRLK3 ALK3 Bone morphogenetic protein receptor type-1A Activin receptor-like kinase 3 Serine/threonine-protein kinase receptor R5 CD_antigen=CD292 Flags: Precursor |
| Molecular Weight(MW) | 60198 Da |
| Function | On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for BMP-2 and BMP-4 |
| Tissue Specificity | Highly expressed in skeletal muscle. |
| Cellular Localization | Membrane; Single-pass type I membrane protein |
Application
Western blot analysis of anti-BMPR1A Pab (Cat. #ap2004a) in Saos-2 cell lysate. BMPR1A (arrow) was detected using purified Pab. Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence.| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
