Application
Western blot analysis of C1RL antibody (N-term) in CEM cell line lysates (35ug/lane). C1RL (arrow) was detected using the purified Pab.| Product Name | C1RL Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | C1RL; C1RL1; C1RLP; CLSPA; Complement C1r subcomponent-like protein; C1r-like serine protease analog protein |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:50~100 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | C1RL1 C1RLP CLSPA |
|---|---|
| Alternative Names | C1RL C1RL1 C1RLP CLSPA Complement C1r subcomponent-like protein C1r-like serine protease analog protein |
| Molecular Weight(MW) | 53498 Da |
| Function | Mediates the proteolytic cleavage of HP/haptoglobin in the endoplasmic reticulum |
| Tissue Specificity | Highly expressed in placenta, liver, kidney, pancreas, moderately in lung, spleen, prostate, ovary, colon, and PBL, and weakly in heart, skeletal muscle, thymus, testis, and small intestine. Expressed in PC-3 (prostate adenocarcinoma) and SK-OV-3 (ovary adenocarcinoma) cells, but not in LoVo and HT-29 (colon adenocarcinoma), SMMC7721 (hepatocellular carcinoma), CaoV- 3 (ovary adenocarcinoma), HeLa (cervix epithelioid carcinoma), MCF-7 (breast adenocarcinoma), U-251MG (glioma) or A-549 (lung carcinoma) cells. Widely expressed in myeloid leukemia cell lines, including K-562 (chronic myelogenous leukemia), THP-1 (myelomonocytic leukemia), HL-60 and NB4 (promyelocytic leukemia), and KG-1 (acute myelogenous leukemia) cells. Expressed mainly in the liver and in serum (at protein level) |
| Cellular Localization | Secreted. |
| Entrez Gene | 51279 |
|---|
Application
Western blot analysis of C1RL antibody (N-term) in CEM cell line lysates (35ug/lane). C1RL (arrow) was detected using the purified Pab.| Application Notes | WB:1:50~100 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
