Application
Western blot analysis of CD79B (arrow) using rabbit polyclonal CD79B Antibody (Center) . 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the CD79B gene.Application
CD79B Antibody (Center) western blot analysis in mouse liver tissue lysates (35ug/lane).This demonstrates the CD79B antibody detected the CD79B protein (arrow).| Product Name | CD79B Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CD79B; B29; IGB; B-cell antigen receptor complex-associated protein beta chain; B-cell-specific glycoprotein B29; Ig-beta; Immunoglobulin-associated B29 protein; CD_antigen=CD79b; Flags: Precursor |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | B29 IGB |
|---|---|
| Alternative Names | CD79B B29 IGB B-cell antigen receptor complex-associated protein beta chain B-cell-specific glycoprotein B29 Ig-beta Immunoglobulin-associated B29 protein CD_antigen=CD79b Flags: Precursor |
| Molecular Weight(MW) | 26048 Da |
| Function | Required in cooperation with CD79A for initiation of the signal transduction cascade activated by the B-cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation Enhances phosphorylation of CD79A, possibly by recruiting kinases which phosphorylate CD79A or by recruiting proteins which bind to CD79A and protect it from dephosphorylation |
| Tissue Specificity | B-cells. |
| Cellular Localization | Cell membrane; Single-pass type I membrane protein. Note=Following antigen binding, the BCR has been shown to translocate from detergent-soluble regions of the cell membrane to lipid rafts although signal transduction through the complex can also occur outside lipid rafts (By similarity) |
| Entrez Gene | 974 |
|---|---|
| Nucleotide Accession | NP_001035022.1 |
Application
Western blot analysis of CD79B (arrow) using rabbit polyclonal CD79B Antibody (Center) . 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the CD79B gene.
Application
CD79B Antibody (Center) western blot analysis in mouse liver tissue lysates (35ug/lane).This demonstrates the CD79B antibody detected the CD79B protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
