Application
Western blot analysis of anti-CIR Antibody (C-term) (RB13825) in K562 cell line lysates (35ug/lane). CIR(arrow) was detected using the purified Pab (1:60 dilution).| Product Name | CIR Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CIR1; CIR; Corepressor interacting with RBPJ 1; CBF1-interacting corepressor; Recepin |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:50~100 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | CIR |
|---|---|
| Alternative Names | CIR1 CIR Corepressor interacting with RBPJ 1 CBF1-interacting corepressor Recepin |
| Molecular Weight(MW) | 52313 Da |
| Function | May modulate splice site selection during alternative splicing of pre-mRNAs (By similarity). Regulates transcription and acts as corepressor for RBPJ. Recruits RBPJ to the Sin3-histone deacetylase complex (HDAC). Required for RBPJ-mediated repression of transcription |
| Tissue Specificity | Highly expressed in heart, brain, placenta, liver, skeletal muscle and pancreas |
| Cellular Localization | Nucleus speckle. Cytoplasm, cytoskeleton, centrosome. Note=Co-localizes with NEK6 in the centrosome |
| Entrez Gene | 9541 |
|---|
Application
Western blot analysis of anti-CIR Antibody (C-term) (RB13825) in K562 cell line lysates (35ug/lane). CIR(arrow) was detected using the purified Pab (1:60 dilution).| Application Notes | WB:1:50~100 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
