Application
(LEFT)Western blot analysis of anti-GJA1 Antibody (N-term) in CEM cell line lysates (35ug/lane). GJA1(arrow) was detected using the purified Pab.(RIGHT)Western blot analysis of hGJA1-N121.Connexin in mouse brain tissue lysates (35ug/lane).GJA1 (arrow) was detected using the purified Pab.| Product Name | Connexin 43 Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | GJA1; GJAL; Gap junction alpha-1 protein; Connexin-43; Gap junction 43 kDa heart protein |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | GJAL |
|---|---|
| Alternative Names | GJA1 GJAL Gap junction alpha-1 protein Connexin-43 Gap junction 43 kDa heart protein |
| Molecular Weight(MW) | 43008 Da |
| Function | Gap junction protein that acts as a regulator of bladder capacity. A gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell May play a critical role in the physiology of hearing by participating in the recycling of potassium to the cochlear endolymph. Negative regulator of bladder functional capacity: acts by enhancing intercellular electrical and chemical transmission, thus sensitizing bladder muscles to cholinergic neural stimuli and causing them to contract (By similarity) |
| Tissue Specificity | Expressed in the heart and fetal cochlea. |
| Cellular Localization | Cell membrane; Multi-pass membrane protein. Cell junction, gap junction |
| Entrez Gene | 2697 |
|---|
Application
(LEFT)Western blot analysis of anti-GJA1 Antibody (N-term) in CEM cell line lysates (35ug/lane). GJA1(arrow) was detected using the purified Pab.(RIGHT)Western blot analysis of hGJA1-N121.Connexin in mouse brain tissue lysates (35ug/lane).GJA1 (arrow) was detected using the purified Pab.| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
