CTGF; CCN2; HCS24; IGFBP8; Connective tissue growth factor; CCN family member 2; Hypertrophic chondrocyte-specific protein 24; Insulin-like growth factor-binding protein 8
Key Feature
Clonality
Polyclonal
Isotype
Ig
Host Species
Rabbit
Tested Applications
WB
WB:1:100~500
Species Reactivity
Human
Concentration
1mg/ml
Target Information
Gene Synonyms
CCN2 HCS24 IGFBP8
Alternative Names
CTGF CCN2 HCS24 IGFBP8 Connective tissue growth factor CCN family member 2 Hypertrophic chondrocyte-specific protein 24 Insulin-like growth factor-binding protein 8
Molecular Weight(MW)
38091 Da
Function
Major connective tissue mitoattractant secreted by vascular endothelial cells. Promotes proliferation and differentiation of chondrocytes. Mediates heparin- and divalent cation-dependent cell adhesion in many cell types including fibroblasts, myofibroblasts, endothelial and epithelial cells Enhances fibroblast growth factor-induced DNA synthesis
Tissue Specificity
Expressed in bone marrow and thymic cells. Also expressed one of two Wilms tumors tested
Western blot analysis of CTGF Antibody (C-term) in NCI-H460 cell line lysates (35ug/lane). CTGF (arrow) was detected using the purified Pab.
Application Notes
WB:1:100~500
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.