Application
CTDSP2 Antibody (N-term) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the CTDSP2 antibody detected the CTDSP2 protein (arrow).| Product Name | CTDSP2 Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CTDSP2; NIF2; OS4; SCP2; Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2; Nuclear LIM interactor-interacting factor 2; Protein OS-4; Small C-terminal domain phosphatase 2; Small CTD phosphatase 2 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | NIF2 OS4 SCP2 |
|---|---|
| Alternative Names | CTDSP2 NIF2 OS4 SCP2 Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2 Nuclear LIM interactor-interacting factor 2 Protein OS-4 Small C-terminal domain phosphatase 2 Small CTD phosphatase 2 |
| Molecular Weight(MW) | 30664 Da |
| Function | Preferentially catalyzes the dephosphorylation of 'Ser- 5' within the tandem 7 residues repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation. Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells. May contribute to the development of sarcomas |
| Tissue Specificity | Expression is restricted to non-neuronal tissues. Highest expression in pancreas and lowest in liver |
| Cellular Localization | Nucleus (By similarity). |
| Entrez Gene | 10106 |
|---|---|
| Nucleotide Accession | NP_005721.3 |
Application
CTDSP2 Antibody (N-term) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the CTDSP2 antibody detected the CTDSP2 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
