DLGAP5; DLG7; KIAA0008; Disks large-associated protein 5; Discs large homolog 7; Disks large-associated protein DLG7; Hepatoma up-regulated protein
Key Feature
Clonality
Polyclonal
Isotype
Ig
Host Species
Rabbit
Tested Applications
WB
WB:1:50~100
Species Reactivity
Human
Concentration
1mg/ml
Target Information
Gene Synonyms
DLG7 KIAA0008
Alternative Names
DLGAP5 DLG7 KIAA0008 Disks large-associated protein 5 Discs large homolog 7 Disks large-associated protein DLG7 Hepatoma up-regulated protein
Molecular Weight(MW)
95115 Da
Function
Potential cell cycle regulator that may play a role in carcinogenesis of cancer cells. Mitotic phosphoprotein regulated by the ubiquitin-proteasome pathway. Key regulator of adherens junction integrity and differentiation that may be involved in CDH1-mediated adhesion and signaling in epithelial cells
Tissue Specificity
Abundantly expressed in fetal liver. Expressed at lower levels in bone marrow, testis, colon, and placenta
Cellular Localization
Nucleus. Cytoplasm. Cytoplasm, cytoskeleton, spindle. Note=Localizes to the spindle in mitotic cells Colocalizes with CDH1 at sites of cell-cell contact in intestinal epithelial cells
Western blot analysis of anti-DLG7 Antibody (N-term) in Ramos cell line lysates (35ug/lane). DLG7(arrow) was detected using the purified Pab.
Application Notes
WB:1:50~100
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.