Application
DUSP26 Antibody (Center) western blot analysis in MDA-MB435 cell line lysates (35ug/lane).This demonstrates the DUSP26 antibody detected the DUSP26 protein (arrow).Application
DUSP26 Antibody (Center) flow cytometric analysis of MDA-MB435 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.| Product Name | DUSP26 Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | DUSP26; DUSP24; LDP4; MKP8; NATA1; SKRP3; Dual specificity protein phosphatase 26; Dual specificity phosphatase SKRP3; Low-molecular-mass dual-specificity phosphatase 4; Mitogen-activated protein kinase phosphatase 8; Novel amplified gene in thyroid anapla |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBFC |
| WB:1:100~500 FC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | DUSP24 LDP4 MKP8 NATA1 SKRP3 |
|---|---|
| Alternative Names | DUSP26 DUSP24 LDP4 MKP8 NATA1 SKRP3 Dual specificity protein phosphatase 26 Dual specificity phosphatase SKRP3 Low-molecular-mass dual-specificity phosphatase 4 Mitogen-activated protein kinase phosphatase 8 Novel amplified gene in thyroid anapla |
| Molecular Weight(MW) | 23946 Da |
| Function | Inactivates MAPK1 and MAPK3 which leads to dephosphorylation of heat shock factor protein 4 and a reduction in its DNA-binding activity. Inhibits MAP kinase p38 by dephosphorylating it and inhibits p38-mediated apoptosis in anaplastic thyroid cancer cells. Can also induce activation of MAP kinase p38 and c-Jun N-terminal kinase (JNK) |
| Tissue Specificity | Brain. In the brain it is expressed ubiquitously except in the hippocampus. Expressed in embryonal cancers (retinoblastoma, neuroepithilioma and neuroblastoma) and in anaplatic thyroid cancer |
| Cellular Localization | Cytoplasm. Nucleus. Golgi apparatus. |
| Entrez Gene | 78986 |
|---|---|
| Nucleotide Accession | NP_076930.1 |
Application
DUSP26 Antibody (Center) western blot analysis in MDA-MB435 cell line lysates (35ug/lane).This demonstrates the DUSP26 antibody detected the DUSP26 protein (arrow).
Application
DUSP26 Antibody (Center) flow cytometric analysis of MDA-MB435 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.| Application Notes | WB:1:100~500 FC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
