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ELAVL1 Antibody

Catalog Number:OM232089
OM232089
Discount Price
OM232089-100ul
1~2 Week
100ul
OM232089-50ul
50ul
OM232089-20ul
20ul
1~2 Week
Product Profile
Product Name ELAVL1 Antibody
Antibody Type Primary Antibodies
Key Feature
Clonality Polyclonal
Isotype Ig
Host Species Rabbit
Tested Applications WBIHCFC
WB:1:100~500 IHC
Species Reactivity Human
Concentration 1mg/ml
Target Information
Gene Synonyms HUR
Alternative Names ELAVL1
HUR
ELAV-like protein 1
Hu-antigen R
Molecular Weight(MW) 36092 Da
Function Involved in 3'-UTR ARE-mediated MYC stabilization. Binds avidly to the AU-rich element in FOS and IL3/interleukin-3 mRNAs In the case of the FOS AU-rich element, HUR binds to a core element of 27 nucleotides that contain AUUUA, AUUUUA and AUUUUUA motifs. Binds preferentially to the 5'-UUUU[AG]UUU-3' motif in vitro
Tissue Specificity Ubiquitous.
Cellular Localization Cytoplasm. Nucleus. Note=Translocates into the cytoplasm following phosphorylation by MAPKAPK2
Database Links
Entrez Gene 1994
Application

Application

Western blot analysis of ELAVL1 Antibody in Hela, Jurkat, CEM, Ramos cell line lysates (35ug/lane). ELAVL1 (arrow) was detected using the purified Pab.

Application

Formalin-fixed and paraffin-embedded human brain tissue reacted with ELAVL1 Antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

Application

ELAVL1 Antibody flow cytometry analysis of Jurkat cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Application

Western blot analysis of ELAVL1 (arrow) using rabbit polyclonal ELAVL1 Antibody . 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the ELAVL1 gene.
Application Notes WB:1:100~500 IHC
Additional Information
Form Liquid
Storage Instructions For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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