ESRRA, ERR1, ESRL1, NR3B1, Steroid hormone receptor ERR1, Estrogen receptor-like 1;Nuclear receptor subfamily 3 group B member 1
Key Feature
Clonality
Monoclonal
Clone Number
EPR46Y
Host Species
Rabbit
Tested Applications
WB
WB:1:2500~5000
Species Reactivity
Human
Concentration
1mg/ml
Target Information
Gene Synonyms
ERR1 ESRL1 NR3B1
Alternative Names
ESRRA ERR1 ESRL1 NR3B1 Steroid hormone receptor ERR1 Estrogen receptor-like 1 Nuclear receptor subfamily 3 group B member 1
Molecular Weight(MW)
45510 Da
Function
Binds to an ERR-alpha response element (ERRE) containing a single consensus half-site, 5'-TNAAGGTCA-3'. Can bind to the medium-chain acyl coenzyme A dehydrogenase (MCAD) response element NRRE-1 and may act as an important regulator of MCAD promoter Binds to the C1 region of the lactoferrin gene promoter. Requires dimerization and the coactivator, PGC-1A, for full activity. The ERRalpha/PGC1alpha complex is a regulator of energy metabolism
Tissue Specificity
A synthetic peptide corresponding to residues near the N-terminus of human ERRalpha was used as an immunogen.