Application
EVI1 Antibody (N-term) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the EVI1 antibody detected the EVI1 protein (arrow).| Product Name | EVI1 Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | MECOM; EVI1; MDS1 and EVI1 complex locus protein EVI1; Ecotropic virus integration site 1 protein homolog |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | EVI1 |
|---|---|
| Alternative Names | MECOM EVI1 MDS1 and EVI1 complex locus protein EVI1 Ecotropic virus integration site 1 protein homolog |
| Molecular Weight(MW) | 118276 Da |
| Function | Functions as a transcriptional regulator binding to DNA sequences in the promoter region of target genes and regulating positively or negatively their expression. Oncogene which plays a role in development, cell proliferation and differentiation. May also play a role in apoptosis through regulation of the JNK and TGF-beta signaling. Involved in hematopoiesis |
| Tissue Specificity | This EVI1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human EVI1. |
| Cellular Localization | Nucleus. Nucleus speckle. |
| Entrez Gene | 2122 |
|---|---|
| Nucleotide Accession | NP_001098547.3 NP_001098548.2 |
Application
EVI1 Antibody (N-term) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the EVI1 antibody detected the EVI1 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
