Western blot analysis of FCAR (arrow) using rabbit polyclonal FCAR Antibody (Center) . 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the FCAR gene.
FCAR CD89 Immunoglobulin alpha Fc receptor CD_antigen=CD89 Flags: Precursor
Molecular Weight(MW)
32265 Da
Function
Binds to the Fc region of immunoglobulins alpha. Mediates several functions including cytokine production
Tissue Specificity
Isoform A.1, isoform A.2 and isoform A.3 are differentially expressed between blood and mucosal myeloid cells Isoform A.1, isoform A.2 and isoform A.3 are expressed in monocytes. Isoform A.1 and isoform A.2 are expressed in alveolar macrophages; however only one isoform is expressed at alveolar macrophages surfaces
Cellular Localization
Isoform A.1: Cell membrane; Single-pass type I membrane protein Isoform A.3: Cell membrane; Single-pass type I membrane protein Isoform B-delta-S2: Secreted.
Western blot analysis of FCAR (arrow) using rabbit polyclonal FCAR Antibody (Center) . 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the FCAR gene.
Application Notes
WB:1:100~500
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.