Application
GGCX Antibody (Center) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the GGCX antibody detected the GGCX protein (arrow).Application
GGCX Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of GGCX Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.| Product Name | GGCX Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | GC |
|---|---|
| Alternative Names | GGCX GC Vitamin K-dependent gamma-carboxylase Gamma-glutamyl carboxylase Peptidyl-glutamate 4-carboxylase Vitamin K gamma glutamyl carboxylase |
| Molecular Weight(MW) | 87561 Da |
| Function | Mediates the vitamin K-dependent carboxylation of glutamate residues to calcium-binding gamma-carboxyglutamate (Gla) residues with the concomitant conversion of the reduced hydroquinone form of vitamin K to vitamin K epoxide |
| Tissue Specificity | This GGCX antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 555-585 amino acids from the Central region of human GGCX. |
| Cellular Localization | Endoplasmic reticulum membrane; Multi-pass membrane protein |
| Entrez Gene | 2677 |
|---|---|
| Nucleotide Accession | NP_000812.2 |
Application
GGCX Antibody (Center) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the GGCX antibody detected the GGCX protein (arrow).
Application
GGCX Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of GGCX Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
