Application
GLS2 Antibody (C-term E513) western blot analysis in mouse brain tissue lysates (35ug/lane).This demonstrates the GLS2 antibody detected the GLS2 protein (arrow).Application
GLS2 antibody(C-term E513) immunohistochemistry analysis in formalin fixed and paraffin embedded human hepatocarcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the GLS2 antibody(C-term E513) for immunohistochemistry. Clinical relevance has not been evaluated.| Product Name | GLS2 Antibody (C-term E513) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | GLS2; GA; Glutaminase liver isoform, mitochondrial; L-glutaminase; L-glutamine amidohydrolase |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | GA |
|---|---|
| Alternative Names | GLS2 GA Glutaminase liver isoform mitochondrial L-glutaminase L-glutamine amidohydrolase |
| Molecular Weight(MW) | 66323 Da |
| Function | Plays an important role in the regulation of glutamine catabolism. Promotes mitochondrial respiration and increases ATP generation in cells by catalyzing the synthesis of glutamate and alpha-ketoglutarate. Increases cellular anti-oxidant function via NADH and glutathione production. May play a role in preventing tumor proliferation |
| Tissue Specificity | Highly expressed in liver. Expressed in brain and pancreas. Not observed in heart, placenta, lung, skeletal muscle and kidney. Expression is significantly reduced in hepatocellular carcinomas |
| Cellular Localization | Mitochondrion. |
| Entrez Gene | 27165 |
|---|---|
| Nucleotide Accession | NP_037399.2 |
Application
GLS2 Antibody (C-term E513) western blot analysis in mouse brain tissue lysates (35ug/lane).This demonstrates the GLS2 antibody detected the GLS2 protein (arrow).
Application
GLS2 antibody(C-term E513) immunohistochemistry analysis in formalin fixed and paraffin embedded human hepatocarcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the GLS2 antibody(C-term E513) for immunohistochemistry. Clinical relevance has not been evaluated.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
