Application
GLYAT Antibody (Center) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the GLYAT antibody detected the GLYAT protein (arrow).Application
GLYAT Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of GLYAT Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.| Product Name | GLYAT Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | GLYAT; ACGNAT; CAT; GAT; Glycine N-acyltransferase; Acyl-CoA:glycine N-acyltransferase; Aralkyl acyl-CoA N-acyltransferase; Aralkyl acyl-CoA:amino acid N-acyltransferase; Benzoyl-coenzyme A:glycine N-acyltransferase; Glycine N-benzoyltransferase; HRP-1(CLP |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | ACGNAT CAT GAT |
|---|---|
| Alternative Names | GLYAT ACGNAT CAT GAT Glycine N-acyltransferase Acyl-CoA:glycine N-acyltransferase Aralkyl acyl-CoA N-acyltransferase Aralkyl acyl-CoA:amino acid N-acyltransferase Benzoyl-coenzyme A:glycine N-acyltransferase Glycine N-benzoyltransferase HRP-1(CLP |
| Molecular Weight(MW) | 33924 Da |
| Function | Mitochondrial acyltransferase which transfers an acyl group to the N-terminus of glycine and glutamine, although much less efficiently. Can conjugate numerous substrates to form a variety of N-acylglycines, with a preference for benzoyl-CoA over phenylacetyl-CoA as acyl donors. Thereby detoxify xenobiotics, such as benzoic acid or salicylic acid, and endogenous organic acids, such as isovaleric acid |
| Tissue Specificity | Predominantly expressed in liver (at protein level) and kidney. Down-regulated in hepatocellular carcinoma and other liver cancers |
| Cellular Localization | Mitochondrion. |
| Entrez Gene | 10249 |
|---|---|
| Nucleotide Accession | NP_964011.2 NP_005829.3 |
Application
GLYAT Antibody (Center) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the GLYAT antibody detected the GLYAT protein (arrow).
Application
GLYAT Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of GLYAT Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
