Application
Western blot analysis of anti-GRK7 Antibody (C-term) in HL60 cell line lysates (35ug/lane). GPRK7 (arrow) was detected using the purified Pab.Application
Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.| Product Name | GRK7 Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | GRK7; GPRK7; G protein-coupled receptor kinase 7; G protein-coupled receptor kinase GRK7 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | GPRK7 |
|---|---|
| Alternative Names | GRK7 GPRK7 G protein-coupled receptor kinase 7 G protein-coupled receptor kinase GRK7 |
| Molecular Weight(MW) | 62212 Da |
| Function | Retina-specific kinase involved in the shutoff of the photoresponse and adaptation to changing light conditions via cone opsin phosphorylation, including rhodopsin (RHO) |
| Tissue Specificity | Retinal cones, outer and inner segments. |
| Cellular Localization | Membrane; Lipid-anchor. |
| Entrez Gene | 131890 |
|---|
Application
Western blot analysis of anti-GRK7 Antibody (C-term) in HL60 cell line lysates (35ug/lane). GPRK7 (arrow) was detected using the purified Pab.
Application
Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
