Application
Western blot analysis of HBO1/MYST2 (arrow) using rabbit polyclonal HBO1/MYST2 Antibody (N-term) .293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the HBO1/MYST2 gene (Lane 2) (Origene Technologies).Application
Formalin-fixed and paraffin-embedded human testis tissue reacted with HBO1/MYST2 antibody (N-term) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.Application
HBO1/MYST2 Antibody (N-term) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the HBO1/MYST2 antibody detected the HBO1/MYST2 protein (arrow).| Product Name | HBO1/MYST2 Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | KAT7; HBO1; HBOa; MYST2; Histone acetyltransferase KAT7; Histone acetyltransferase binding to ORC1; Lysine acetyltransferase 7; MOZ, YBF2/SAS3, SAS2 and TIP60 protein 2 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:50~100 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | HBO1 HBOa MYST2 |
|---|---|
| Alternative Names | KAT7 HBO1 HBOa MYST2 Histone acetyltransferase KAT7 Histone acetyltransferase binding to ORC1 Lysine acetyltransferase 7 MOZ YBF2/SAS3 SAS2 and TIP60 protein 2 |
| Molecular Weight(MW) | 70642 Da |
| Function | Component of the HBO1 complex which has a histone H4- specific acetyltransferase activity, a reduced activity toward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo. Through chromatin acetylation it may regulate DNA replication and act as a coactivator of TP53-dependent transcription. Specifically represses AR-mediated transcription |
| Tissue Specificity | Ubiquitously expressed, with highest levels in testis |
| Cellular Localization | Nucleus, nucleoplasm. |
| Entrez Gene | 11143 |
|---|
Application
Western blot analysis of HBO1/MYST2 (arrow) using rabbit polyclonal HBO1/MYST2 Antibody (N-term) .293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the HBO1/MYST2 gene (Lane 2) (Origene Technologies).
Application
Formalin-fixed and paraffin-embedded human testis tissue reacted with HBO1/MYST2 antibody (N-term) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Application
HBO1/MYST2 Antibody (N-term) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the HBO1/MYST2 antibody detected the HBO1/MYST2 protein (arrow).| Application Notes | WB:1:50~100 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
