Application
HEMGN Antibody (C-term) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the HEMGN antibody detected the HEMGN protein (arrow).| Product Name | HEMGN Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | HEMGN; EDAG; NDR; Hemogen; Erythroid differentiation-associated gene protein; Hemopoietic gene protein; Negative differentiation regulator protein |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | EDAG NDR |
|---|---|
| Alternative Names | HEMGN EDAG NDR Hemogen Erythroid differentiation-associated gene protein Hemopoietic gene protein Negative differentiation regulator protein |
| Molecular Weight(MW) | 55341 Da |
| Function | Regulates the proliferation and differentiation of hematopoietic cells. Overexpression block the TPA-induced megakaryocytic differentiation in the K562 cell model. May also prevent cell apoptosis through the activation of the nuclear factor-kappa B (NF-kB) |
| Tissue Specificity | Expressed in hematopoietic precursor cells (at protein level). Detected in CD34+ and K-562 leukemia cell lines (at protein level). Expressed in bone marrow, testis, thymus. Also expressed in thymus and thyroid tumors, non-Hodgkin lymphoma, various leukemia cell lines, peripheral blood mononuclear cells (PBMCs) and bone marrow mononuclear cells (BMMCs) of patients with leukemia |
| Cellular Localization | Nucleus. |
| Entrez Gene | 55363 |
|---|---|
| Nucleotide Accession | NP_932095.1 NP_060907.2 |
Application
HEMGN Antibody (C-term) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the HEMGN antibody detected the HEMGN protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
