Application
HEXIM1 Antibody (N-term) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the HEXIM1 antibody detected the HEXIM1 protein (arrow).Application
HEXIM1 Antibody (N-term) western blot analysis in mouse NIH-3T3 cell line lysates (35ug/lane).This demonstrates the HEXIM1 antibody detected the HEXIM1 protein (arrow).Application
HEXIM1 Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human colon tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of HEXIM1 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Product Name | HEXIM1 Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | HEXIM1; CLP1; EDG1; HIS1; MAQ1; Protein HEXIM1; Cardiac lineage protein 1; Estrogen down-regulated gene 1 protein; Hexamethylene bis-acetamide-inducible protein 1; Menage a quatre protein 1 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | CLP1 EDG1 HIS1 MAQ1 |
|---|---|
| Alternative Names | HEXIM1 CLP1 EDG1 HIS1 MAQ1 Protein HEXIM1 Cardiac lineage protein 1 Estrogen down-regulated gene 1 protein Hexamethylene bis-acetamide-inducible protein 1 Menage a quatre protein 1 |
| Molecular Weight(MW) | 40623 Da |
| Function | Transcriptional regulator which functions as a general RNA polymerase II transcription inhibitor. In cooperation with 7SK snRNA sequesters P-TEFb in a large inactive 7SK snRNP complex preventing RNA polymerase II phosphorylation and subsequent transcriptional elongation. May also regulate NF-kappa-B, ESR1, NR3C1 and CIITA-dependent transcriptional activity |
| Tissue Specificity | Ubiquitously expressed with higher expression in placenta. HEXIM1 and HEXIM2 are differentially expressed Expressed in endocrine tissues |
| Cellular Localization | Nucleus. Cytoplasm. Note=Binds alpha- importin and is mostly nuclear |
| Entrez Gene | 10614 |
|---|---|
| Nucleotide Accession | NP_006451.1 |
Application
HEXIM1 Antibody (N-term) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the HEXIM1 antibody detected the HEXIM1 protein (arrow).
Application
HEXIM1 Antibody (N-term) western blot analysis in mouse NIH-3T3 cell line lysates (35ug/lane).This demonstrates the HEXIM1 antibody detected the HEXIM1 protein (arrow).
Application
HEXIM1 Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human colon tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of HEXIM1 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
