Application
HEXIM1 antibody (Center) western blot analysis in mouse liver tissue lysates (35ug/lane).This demonstrates the HEXIM1 antibody detected the HEXIM1 protein (arrow).Application
HEXIM1 antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human placenta tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of HEXIM1 antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.| Product Name | HEXIM1 antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | HEXIM1; CLP1; EDG1; HIS1; MAQ1; Protein HEXIM1; Cardiac lineage protein 1; Estrogen down-regulated gene 1 protein; Hexamethylene bis-acetamide-inducible protein 1; Menage a quatre protein 1 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | CLP1 EDG1 HIS1 MAQ1 |
|---|---|
| Alternative Names | HEXIM1 CLP1 EDG1 HIS1 MAQ1 Protein HEXIM1 Cardiac lineage protein 1 Estrogen down-regulated gene 1 protein Hexamethylene bis-acetamide-inducible protein 1 Menage a quatre protein 1 |
| Molecular Weight(MW) | 40623 Da |
| Function | Transcriptional regulator which functions as a general RNA polymerase II transcription inhibitor. In cooperation with 7SK snRNA sequesters P-TEFb in a large inactive 7SK snRNP complex preventing RNA polymerase II phosphorylation and subsequent transcriptional elongation. May also regulate NF-kappa-B, ESR1, NR3C1 and CIITA-dependent transcriptional activity |
| Tissue Specificity | Ubiquitously expressed with higher expression in placenta. HEXIM1 and HEXIM2 are differentially expressed Expressed in endocrine tissues |
| Cellular Localization | Nucleus. Cytoplasm. Note=Binds alpha- importin and is mostly nuclear |
| Entrez Gene | 10614 |
|---|---|
| Nucleotide Accession | NP_006451.1 |
Application
HEXIM1 antibody (Center) western blot analysis in mouse liver tissue lysates (35ug/lane).This demonstrates the HEXIM1 antibody detected the HEXIM1 protein (arrow).
Application
HEXIM1 antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human placenta tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of HEXIM1 antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
