Application
A. Western blot analysis on SH-SY-5Y cell lysate using anti-huntingtin RabMAb (Cat. #AJ1385a), dilution 1:10,000.Application
B. Immunohistochemical analysis of paraffin-embedded human brain tissue using RabMAb. (Cat. #AJ1385a).| Product Name | Huntingtin (HTT) Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | HTT, HD, IT15, Huntingtin, Huntington disease protein |
| Clonality | Monoclonal |
|---|---|
| Clone Number | EP867Y |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:1000~10000 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | HD IT15 |
|---|---|
| Alternative Names | HTT HD IT15 Huntingtin Huntington disease protein |
| Molecular Weight(MW) | 347603 Da |
| Function | May play a role in microtubule-mediated transport or vesicle function |
| Tissue Specificity | Expressed in the brain cortex (at protein level). Widely expressed with the highest level of expression in the brain (nerve fibers, varicosities, and nerve endings). In the brain, the regions where it can be mainly found are the cerebellar cortex, the neocortex, the striatum, and the hippocampal formation |
| Cellular Localization | Cytoplasm. Nucleus. Note=The mutant Huntingtin protein colocalizes with AKAP8L in the nuclear matrix of Huntington disease neurons |
| Entrez Gene | 3064 |
|---|
Application
A. Western blot analysis on SH-SY-5Y cell lysate using anti-huntingtin RabMAb (Cat. #AJ1385a), dilution 1:10,000.
Application
B. Immunohistochemical analysis of paraffin-embedded human brain tissue using RabMAb. (Cat. #AJ1385a).| Application Notes | WB:1:1000~10000 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. |
