Application
Western blot analysis of IL26 Antibody (Center) in HL-60 cell line lysates (35ug/lane). IL26 (arrow) was detected using the purified Pab.| Product Name | IL26 Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | IL26; AK155; Interleukin-26; Protein AK155 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | AK155 |
|---|---|
| Alternative Names | IL26 AK155 Interleukin-26 Protein AK155 |
| Molecular Weight(MW) | 19843 Da |
| Function | May play a role in local mechanisms of mucosal immunity and seems to have a proinflammatory function. May play a role in inflammatory bowel disease. Activates STAT1 and STAT3, MAPK1/3 (ERK1/2), JUN and AKT. Induces expression of SOCS3, TNF-alpha and IL-8, secretion of IL-8 and IL-10 and surface expression of ICAM1 Decreases proliferation of intestinal epithelial cells. Is inhibited by heparin |
| Tissue Specificity | Expressed in HVS transformed T-cells but not other T-cell lines or primary stimulated T-cells. Expressed in colonic T-cells including Th17 inflammatory T-cells; the expression is significantly increased in serum of patients with Crohn's disease (at protein level) |
| Cellular Localization | Secreted. |
| Entrez Gene | 55801 |
|---|
Application
Western blot analysis of IL26 Antibody (Center) in HL-60 cell line lysates (35ug/lane). IL26 (arrow) was detected using the purified Pab.| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
