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ITGA5 Antibody (Center)

Catalog Number:OM236161
OM236161
Discount Price
OM236161-100ul
1~2 Week
100ul
OM236161-50ul
50ul
OM236161-20ul
20ul
1~2 Week
Product Profile
Product Name ITGA5 Antibody (Center)
Antibody Type Primary Antibodies
Antigen Alias ITGA5; FNRA; Integrin alpha-5; CD49 antigen-like family member E; Fibronectin receptor subunit alpha; Integrin alpha-F; VLA-5; CD_antigen=CD49e; Integrin alpha-5 heavy chain; Integrin alpha-5 light chain
Key Feature
Clonality Polyclonal
Isotype Ig
Host Species Rabbit
Tested Applications WBIHC
WB:1:100~500 IHC
Species Reactivity Human
Concentration 1mg/ml
Target Information
Gene Synonyms FNRA
Alternative Names ITGA5
FNRA
Integrin alpha-5
CD49 antigen-like family member E
Fibronectin receptor subunit alpha
Integrin alpha-F
VLA-5
CD_antigen=CD49e
Integrin alpha-5 heavy chain
Integrin alpha-5 light chain
Molecular Weight(MW) 114536 Da
Function Integrin alpha-5/beta-1 is a receptor for fibronectin and fibrinogen. It recognizes the sequence R-G-D in its ligands In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions
Tissue Specificity This ITGA5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 574-602 amino acids from the Central region of human ITGA5.
Cellular Localization Membrane; Single-pass type I membrane protein
Database Links
Entrez Gene 3678
Nucleotide Accession NP_002196
Application

Application

Western blot analysis of ITGA5 (arrow) using rabbit polyclonal ITGA5 Antibody (Center) . 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the ITGA5 gene.

Application

ITGA5 Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human placenta tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of ITGA5 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.

Application

ITGA5 Antibody (Center) western blot analysis in human uterine tumor and mouse bladder tissue lysates (35ug/lane).This demonstrates the ITGA5 antibody detected the ITGA5 protein (arrow).
Application Notes WB:1:100~500 IHC
Additional Information
Form Liquid
Storage Instructions For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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