KDM3B; C5orf7; JHDM2B; JMJD1B; KIAA1082; Lysine-specific demethylase 3B; JmjC domain-containing histone demethylation protein 2B; Jumonji domain-containing protein 1B; Nuclear protein 5qNCA
Key Feature
Clonality
Polyclonal
Isotype
Ig
Host Species
Rabbit
Tested Applications
WB
WB:1:250~500
Species Reactivity
Human
Concentration
1mg/ml
Target Information
Gene Synonyms
C5orf7 JHDM2B JMJD1B KIAA1082
Alternative Names
KDM3B C5orf7 JHDM2B JMJD1B KIAA1082 Lysine-specific demethylase 3B JmjC domain-containing histone demethylation protein 2B Jumonji domain-containing protein 1B Nuclear protein 5qNCA
Molecular Weight(MW)
191581 Da
Function
Histone demethylase that specifically demethylates 'Lys- 9' of histone H3, thereby playing a central role in histone code Demethylation of Lys residue generates formaldehyde and succinate May have tumor suppressor activity
Tissue Specificity
Ubiquitous. Highly expressed in placenta, skeletal muscle, kidney, heart and liver
Western blot analysis of anti-JMJD1B (N-term) Pab in Ramos cell line lysate. JMJD1B (N-term)(arrow) was detected using the purified Pab.
Application Notes
WB:1:250~500
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.