Application
JMJD2C Antibody (C-term) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the JMJD2C antibody detected the JMJD2C protein (arrow).Application
JMJD2C Antibody (C-term) flow cytometric analysis of K562 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.| Product Name | JMJD2C Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | KDM4C; GASC1; JHDM3C; JMJD2C; KIAA0780; Lysine-specific demethylase 4C; Gene amplified in squamous cell carcinoma 1 protein; JmjC domain-containing histone demethylation protein 3C; Jumonji domain-containing protein 2C |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBFC |
| WB:1:100~500 FC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | GASC1 JHDM3C JMJD2C KIAA0780 |
|---|---|
| Alternative Names | KDM4C GASC1 JHDM3C JMJD2C KIAA0780 Lysine-specific demethylase 4C Gene amplified in squamous cell carcinoma 1 protein JmjC domain-containing histone demethylation protein 3C Jumonji domain-containing protein 2C |
| Molecular Weight(MW) | 119982 Da |
| Function | Histone demethylase that specifically demethylates 'Lys- 9' and 'Lys-36' residues of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27' nor H4 'Lys-20'. Demethylates trimethylated H3 'Lys-9' and H3 'Lys-36' residue, while it has no activity on mono- and dimethylated residues. Demethylation of Lys residue generates formaldehyde and succinate |
| Tissue Specificity | Overexpressed in several esophageal squamous cell carcinomas (ESCs) |
| Cellular Localization | Nucleus (By similarity). |
| Entrez Gene | 23081 |
|---|---|
| Nucleotide Accession | NP_001140167.1 NP_001140166.1 NP_001140168.1 |
Application
JMJD2C Antibody (C-term) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the JMJD2C antibody detected the JMJD2C protein (arrow).
Application
JMJD2C Antibody (C-term) flow cytometric analysis of K562 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.| Application Notes | WB:1:100~500 FC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
