Application
KCNJ3 Antibody (C-term) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the KCNJ3 antibody detected the KCNJ3 protein (arrow).Application
KCNJ3 Antibody (C-term) western blot analysis in mouse stomach tissue lysates (35ug/lane).This demonstrates the KCNJ3 antibody detected the KCNJ3 protein (arrow).Application
KCNJ3 Antibody (C-term) (AP14225b)immunohistochemistry analysis in formalin fixed and paraffin embedded human cerebellum tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of KCNJ3 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Product Name | KCNJ3 Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | KCNJ3; GIRK1; G protein-activated inward rectifier potassium channel 1; Inward rectifier K(+) channel Kir3.1; Potassium channel, inwardly rectifying subfamily J member 3 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | GIRK1 |
|---|---|
| Alternative Names | KCNJ3 GIRK1 G protein-activated inward rectifier potassium channel 1 Inward rectifier K(+) channel Kir3.1 Potassium channel inwardly rectifying subfamily J member 3 |
| Molecular Weight(MW) | 56603 Da |
| Function | This potassium channel is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. This receptor plays a crucial role in regulating the heartbeat |
| Tissue Specificity | This KCNJ3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 389-418 amino acids from the C-terminal region of human KCNJ3. |
| Cellular Localization | Membrane; Multi-pass membrane protein. |
| Entrez Gene | 3760 |
|---|---|
| Nucleotide Accession | NP_002230.1 |
Application
KCNJ3 Antibody (C-term) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the KCNJ3 antibody detected the KCNJ3 protein (arrow).
Application
KCNJ3 Antibody (C-term) western blot analysis in mouse stomach tissue lysates (35ug/lane).This demonstrates the KCNJ3 antibody detected the KCNJ3 protein (arrow).
Application
KCNJ3 Antibody (C-term) (AP14225b)immunohistochemistry analysis in formalin fixed and paraffin embedded human cerebellum tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of KCNJ3 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
