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LPL Antibody (Center)

Catalog Number:OM237354
OM237354
Discount Price
OM237354-100ul
1~2 Week
100ul
OM237354-50ul
50ul
OM237354-20ul
20ul
1~2 Week
Product Profile
Product Name LPL Antibody (Center)
Antibody Type Primary Antibodies
Key Feature
Clonality Polyclonal
Isotype Ig
Host Species Rabbit
Tested Applications WBIHCFC
WB:1:100~500 IHC
Species Reactivity Human
Concentration 1mg/ml
Target Information
Gene Synonyms LIPD
Alternative Names LPL
LIPD
Lipoprotein lipase
Molecular Weight(MW) 53162 Da
Function The primary function of this lipase is the hydrolysis of triglycerides of circulating chylomicrons and very low density lipoproteins (VLDL). Binding to heparin sulfate proteogylcans at the cell surface is vital to the function. The apolipoprotein, APOC2, acts as a coactivator of LPL activity in the presence of lipids on the luminal surface of vascular endothelium (By similarity)
Tissue Specificity This LPL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 299-327 amino acids from the Central region of human LPL.
Cellular Localization Cell membrane (By similarity); Lipid-anchor, GPI-anchor (By similarity). Secreted (By similarity). Note=Locates to the plasma membrane of microvilli of hepatocytes with triacyl- glycerol-rich lipoproteins (TRL). Some of the bound LPL is then internalized and located inside non-coated endocytic vesicles (By similarity)
Database Links
Entrez Gene 4023
Nucleotide Accession NP_000228.1
Application

Application

LPL Antibody (Center) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the LPL antibody detected the LPL protein (arrow).

Application

LPL Antibody (Center) (AP14170c)immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of LPL Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.

Application

LPL Antibody (Center) flow cytometric analysis of Hela cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Application Notes WB:1:100~500 IHC
Additional Information
Form Liquid
Storage Instructions For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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